Journal: Cerebral Cortex (New York, NY)

Article Title: Long-latency auditory evoked responses across species show increased amplitude during early life

doi: 10.1093/cercor/bhaf274

Figure Lengend Snippet: Time course and location of auditory activation in humans and rats. (a) Time course of activation evoked by the auditory probes in the current source located in the left supratemporal auditory cortex in humans. Significant differences between age groups are indicated by asterisks. (b) Time course of activation evoked by the auditory probes as recorded by the silver wire electrode from the surface of the auditory cortex in rats. (c) MNE source waveforms in the left hemisphere ROI (Heschl’s gyrus, Heschl’s sulcus, and planum temporale) shown for each individual voxel, with separate rows representing the 3 different age groups (see for methods). (d) The location and orientation of the equivalent current dipole (ECD) in humans, fitted at the time point of maximum amplitude for each age group (250 ms for children, 100 ms for adults). (e) Whole-head sensor array with evoked responses in the 3 age groups of humans and 1 sensor enlarged to provide model-free illustration of the timeline of activation. The distribution of sensors used for localizing the ECD is delimited with a dashed line.

Article Snippet: A silver wire recording electrode (Ø 0.5 mm, A-M Systems, WA, USA) was positioned on the surface of the dura and attached to a miniature connector together with ground and reference electrodes.

Techniques: Activation Assay